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Root Cause of Post-Traumatic and Developmental Stress Disorders
Major Depression and Post-traumatic Stress Disorder (PTSD) are among the most common mental health problems
experienced by veterans returning from Iraq and Afghanistan. Alcohol and drug use are also common problems in
troops and veterans who have deployed overseas. Stress is an acknowledged contributor to the development and
progression of each of these conditions. Our research program will investigate the "Root Cause", or biological
basis of these conditions, which we hypothesize is heavily influenced by brain anatomy.
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News Feed
Mobile MRI Arrives in Waco
The VISN 17/CTVHCS Mobile MRI was recently unveiled at the Waco VA with the help of Representative Chet Edwards, Virginia Dupuy (Waco Mayor), Col Wilma Larson (DCCS Darnall Army Medical Center), Bruce Gordon (Director CTVHCS), Tim Shea (Director VISN 17), Suzy Gulliver (COE Director), Keith Young (COE Neuroimaging and Genetics Core Leader) and (Paul Hicks (CTVHCS . The Phillips 3T mobile unit, one of only 3 in existence, will conduct research at Waco, Temple and Fort Hood. The Root Cause of PTSD project 5 will be one of the first projects implemented to study the genetic underpinnings of brain anatomical predisposition to PTSD and Depression.
- View News Story at Dallas Morning News Story (AP Wire). - View More Pictures here. - View the TV News Spot at KCEN News Story. - Posted by Keith Young on Jul 07, 2008 10:37am CDT CTVHCS hosts worlds largest mobile MRI The 3T mobile MRI from Phillips, the worlds largest research-dedicated portable MRI, will be used to perform Mental Health research at the Waco and Temple VA, and at Fort Hood. Root Cause Project 5 is being revised to make use of this unique resource, which will be managed by the VA Center of Excellence for Research on Returning War Veterans. - Posted by Kevin Kastner on Jun 03, 2008 09:06am CDT Summer studentships Available! Applications for 2009 summer studentships are due in Mid-April. more... - Posted by Kevin Kastner on Apr 12, 2008 03:53pm CDT Miller Poster Award Congratulations to Laura Miller for winning the "Best Poster" award! more... - Posted by Kevin Kastner on Mar 03, 2008 04:32pm CST < prev |
Root Cause of PTSD in the News
Check out our article in VA Research Currents. Research news from the u.s. department of veterans affairs.
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Projects
1) Early progression of post-deployment stress disorders
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2) Fluoxetine for post-deployment stress disorder
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3) Serotonin and other genes and biomarkers
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4) Serotonin and other genetic effects on brain anatomy
Inheritance of a variant of the serotonin transporter (SERT-ss) is associated with an enlargement of the pulvinar
nucleus of the thalamus, an important part of the brain's automatic threat detection system, potentially making
these individuals more susceptible to developing PTSD and depression after exposure to combat stress and trauma.
However, the details of which nerve cells and brain chemical systems are involved in PTSD are not known.
This project will expand our previous investigations by studying brain anatomy in post-mortem tissue from depression
and PTSD.
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5) Serotonin and other genetic effects on regional brain anatomy and function
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6) Anatomical and behavioral animal models of developmental stress disorders
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