Root Cause of Post-traumatic and Developmental Stress Disorders

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Root Cause of Post-Traumatic and Developmental Stress Disorders

Major Depression and Post-traumatic Stress Disorder (PTSD) are among the most common mental health problems experienced by veterans returning from Iraq and Afghanistan. Alcohol and drug use are also common problems in troops and veterans who have deployed overseas. Stress is an acknowledged contributor to the development and progression of each of these conditions. Our research program will investigate the "Root Cause", or biological basis of these conditions, which we hypothesize is heavily influenced by brain anatomy. more...

News Feed

Mobile MRI Arrives in Waco
The VISN 17/CTVHCS Mobile MRI was recently unveiled at the Waco VA with the help of Representative Chet Edwards, Virginia Dupuy (Waco Mayor), Col Wilma Larson (DCCS Darnall Army Medical Center), Bruce Gordon (Director CTVHCS), Tim Shea (Director VISN 17), Suzy Gulliver (COE Director), Keith Young (COE Neuroimaging and Genetics Core Leader) and (Paul Hicks (CTVHCS . The Phillips 3T mobile unit, one of only 3 in existence, will conduct research at Waco, Temple and Fort Hood. The Root Cause of PTSD project 5 will be one of the first projects implemented to study the genetic underpinnings of brain anatomical predisposition to PTSD and Depression.
- View News Story at Dallas Morning News Story (AP Wire).
- View More Pictures here.
- View the TV News Spot at KCEN News Story. - Posted by Keith Young on Jul 07, 2008 10:37am CDT
CTVHCS hosts worlds largest mobile MRI
The 3T mobile MRI from Phillips, the worlds largest research-dedicated portable MRI, will be used to perform Mental Health research at the Waco and Temple VA, and at Fort Hood. Root Cause Project 5 is being revised to make use of this unique resource, which will be managed by the VA Center of Excellence for Research on Returning War Veterans. - Posted by Kevin Kastner on Jun 03, 2008 09:06am CDT
Summer studentships Available!
Applications for 2009 summer studentships are due in Mid-April. more... - Posted by Kevin Kastner on Apr 12, 2008 03:53pm CDT
Miller Poster Award
Congratulations to Laura Miller for winning the "Best Poster" award! more... - Posted by Kevin Kastner on Mar 03, 2008 04:32pm CST
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Root Cause of PTSD in the News

Check out our article in VA Research Currents. Research news from the u.s. department of veterans affairs. more...

Projects

1) Early progression of post-deployment stress disorders more...
2) Fluoxetine for post-deployment stress disorder more...
3) Serotonin and other genes and biomarkers more...
4) Serotonin and other genetic effects on brain anatomy more...
5) Serotonin and other genetic effects on regional brain anatomy and function
The brain anatomical changes associated with inheritance of the serotonin transporter short allele most likely affect behavior because they alter activity of the brains limbic system, which is responsible for monitoring and interpreting threatening conditions in the environment. In this project we will use MRI and evoked potentials ("brainwaves") to monitor brain anatomy and function in veterans with PTSD and volunteers. We will also determine the genetic profiles of these subjects. We will then be able to determine whether the serotonin and other genes promote the development fear responses and enhance threat monitoring, potentially contributing to what is observed in PTSD. less...
6) Anatomical and behavioral animal models of developmental stress disorders more...